Gene Expression Counts for Marthandan et al. (2016) RNA-Seq Data

A numeric matrix containing gene expression data from the Marthandan et al. (2016) study (GEO code GSE63577). The data represent normalized (non-transformed) counts for genes across samples.

Usage

counts_example

Format

A numeric matrix with rows corresponding to genes and columns corresponding to samples. Row names indicate gene symbols and column names are sample identifiers.

Source

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE63577

Details

The samples were quality-controlled using FastQC and aligned using kallisto (v0.46.1) against the RefSeq v109 transcriptome. The original dataset had 45 samples, but intermediate time points from HFF and MRC5 were removed.

References

Marthandan S, Priebe S, Baumgart M, Groth M et al. Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts. Biomed Res Int 2015;2015:731938. PMID: 26339636

Marthandan S, Baumgart M, Priebe S, Groth M et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS One 2016;11(5):e0154531. PMID: 27140416