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Example Gene Sets for Cellular Senescence

Source: R/data.R
genesets_example.Rd

Example Gene Sets for Cellular Senescence

Usage

data(genesets_example)

Format

A named list of length 3:

Literature_Senescence

Character vector of gene symbols. A small, curated gene set of commonly reported senescence markers, with directionality (+1 or -1).

REACTOME_Senescence

Character vector of gene symbols. A gene set from the REACTOME_CELLULAR_SENESCENCE MSigDB pathway. No directionality.

HernandezSegura

A data frame with columns gene and direction. A gene set from Hernandez-Segura et al. (2017), with directionality (+1 or -1).

References

Hernandez-Segura A, de Jong TV, Melov S, Guryev V, Campisi J, Demaria M. Unmasking Transcriptional Heterogeneity in Senescent Cells. Curr Biol. 2017 Sep 11;27(17):2652-2660.e4. doi: 10.1016/j.cub.2017.07.033. Epub 2017 Aug 30. PMID: 28844647; PMCID: PMC5788810.