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The markeR package provides tools for evaluating gene signatures across phenotypes in transcriptomics datasets (especially bulk RNA-seq). It implements scoring and enrichment approaches, alongside intuitive visualizations and performance metrics.

Key features:

  • Score-based signature quantification (e.g., median-centered, ssGSEA, ranking)

  • Enrichment analysis using GSEA

  • Visualization of gene expression, scores, and enrichment results

See also

For more information on using the markeR package, check out the markeR Documentation. You can also visit the GitHub Repository for the latest updates and source code.

Author

Maintainer: Rita Martins-Silva rita.silva@gimm.pt (ORCID)

Authors:

  • Alexandre Kaizeler (ORCID) [contributor]

  • Nuno Luís Barbosa-Morais (ORCID) [lead, thesis advisor]